Research & references

The science behind the book.

A curated library of peer-reviewed research supporting the claims in Why Do I Feel Like This? — pulled directly from Dr. Allen's own references. Each card links to the study on PubMed.

Lancet Diabetes & Endocrinol
2023 · Peer-reviewed
Lab Ranges · Thyroid

The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality

Xu Y, Derakhshan A, Hysaj O, et al. A large meta-analysis defining what truly optimal thyroid function looks like, measured by long-term cardiovascular outcomes — not just statistical reference intervals.

Read on PubMed →
J Clin Endocrinol Metab
2018 · Clinical Guideline
Men's Health · TRT

Testosterone Therapy in Men with Hypogonadism: An Endocrine Society Clinical Practice Guideline

Bhasin S, Brito JP, Cunningham GR, et al. The leading clinical guideline used by hormone physicians worldwide to diagnose and treat low testosterone — a foundational reference for the andropause chapter.

Read on PubMed →
JAMA Internal Medicine
2015 · SWAN Study
Women's Health · Menopause

Duration of menopausal vasomotor symptoms over the menopause transition

Avis NE, Crawford SL, Greendale G, et al. The landmark SWAN study showing that hot flashes and night sweats commonly last more than 7 years — directly supporting the perimenopause and menopause chapters.

Read on PubMed →
Menopause
2022 · NAMS Position Statement
Hormone Therapy

The 2022 hormone therapy position statement of The North American Menopause Society

The current professional consensus on modern hormone therapy — including the timing hypothesis, individualized treatment, and reframed cardiovascular and breast cancer risk profiles cited throughout the book.

Read on PubMed →
Archives of Internal Medicine
2000 · Landmark Prevalence Study
Thyroid · Prevalence

The Colorado Thyroid Disease Prevalence Study

Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. A landmark population study showing how commonly thyroid dysfunction goes undiagnosed in patients with "normal" routine labs — central evidence for the Gray Zone framework.

Read on PubMed →
J Clin Endocrinol Metab
2023 · International Guideline
Metabolic · PCOS

2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome

Teede HJ, Tay CT, Laven JJE, et al. The current global consensus on PCOS — covering prevalence, the Rotterdam Criteria, and long-term risks for diabetes, cardiovascular disease, and mood disorders. Basis for the PCOS chapter.

Read on PubMed →
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